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ARPN Journal of Science and Technology >> Volume 7, Issue 1, January 2017

ARPN Journal of Science and Technology

Flavonoids of Phylanthus Niruri as Immunomodulators A Prospect to Animal Disease Control

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Author Lili Zalizar
ISSN 2225-7217
On Pages 529-532
Volume No. 3
Issue No. 5
Issue Date June 01, 2013
Publishing Date June 01, 2013
Keywords P.niruri, immunomodulators,activity and capacity of phagocytosis, antibody titre level


Previously researchers have examined that an arabinogalactan (AG) obtained from Phylanthus spp act as immunomodulator because it appears to stimulate immune system. In this research, we want to examine the potential of flavonoids of P niruri as immunomodulators. Fifteen rats were divided into 5 groups; Group 1 without flavonoids; Group 2 had 1% flavonoids; Group 3 had 2% flavonoids, Group 4 had 3% flavonoids and Group 5 had 4% of flavonoid of body weight of rats. Flavonoids were given for fourteen (14) consecutive days. The results showed P. niruri flavonoids can be as immunomodulators especially as immunostimulators because it can increase the activity and capacity of the phagocytosis. Flavonoids of P.niruri also can increase antibody titer level. Flavonoid of P.niruri does not affect animalsí performance because it does not affect the levels of hemoglobin, erythrocyte total and hematocrit.

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