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ARPN Journal of Science and Technology >> Volume 7, Issue 1, January 2017

ARPN Journal of Science and Technology


Serum Level of Superoxide Dismutase, Malondealdehyde and Uric Acid among Artisans in Cross-River State, Nigeria

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Author Johnson, J. T., Onofiok, U.L, Eyo, R.A, Ekam, V.S, Odey, M. O.
ISSN 2225-7217
On Pages 658-660
Volume No. 2
Issue No. 7
Issue Date August 01, 2012
Publishing Date August 01, 2012
Keywords Superoxide Dismutase, Malondealdehyde, Uric-acid, Artisans.



Abstract

Oxidative stress and oxidative damage to tissues are involved in the path physiology of many diseases. Many occupations, most especially crafts are associated with the generation of high levels of free radicals and hence increased post-oxidant level. This study evaluated the serum level of Superoxide dismutase, Malondealdehyde and uric acid of artisans in Cross-River State, Nigeria. The results reveals that the SOD level in all the artisans did not show any significant change at P<0.05. However, MDA level in mechanics (4.530.25), Welders (4.420.20) and spray painter (4.000.06) where all significantly lower when compared with the control (3.140.09) at P=0.05, thus indicating increased per oxidation but the reveres was the case for carpenters where no change was observed compared with the control. More so, determination of uric acid level showed that mechanics (2.71 0.31), welders (3.980.22), Battery repairers (3.400.37) marked significance difference compared with control (5.860.28) though similar trend was seen in carpenters (5.720.20) and spray painters (4.220.25). All groups of artisans were compared with the control at P=0.05 level of probability. Thus, this work has opened up the occupational hazard associated craft Men or artisans and the possible health implications associated with their jobs and hence recommend more safety guides and increased anti-oxidant nutrients consumptions.


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