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ARPN Journal of Science and Technology >> Volume 7, Issue 2, November 2017

ARPN Journal of Science and Technology

Antimicrobial Activity of Ethanol Extract of Four Indigenous Plants From South Eastern Nigeria

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Author Okwulehie, Ikechukwu Cyriacus and Akanwa, Franklin Eberechukwu
ISSN 2225-7217
On Pages 350-355
Volume No. 3
Issue No. 4
Issue Date May 01, 2013
Publishing Date May 01, 2013
Keywords Laportia ovalifolia, Spondias mombin, Ficus exasperate, Ageratum conyzoides, Antimicrobial properties.


The Antimicrobial properties of the ethanolic leaf extract of four indigenous plants, Laportia ovalifolia, Spondias mombin, Ficus exasperata and Ageratum conyzoides, on four bacterial isolates (Stapshylococcus aureus, P aeruginosa, Escherichia coli, and Salmonella taphi),were investigated, The minimum inhibitory concentration (MIC) of these plants for each of the test organisms was evaluated. The antimicrobial activity of the plant extracts was determined by the Well diffusion method. The ethanolic leaf extract of all the plants inhibited the test organisms. The widest spectrum of antimicrobial activity was recorded for the ethanolic leaf extracts of S. monbin against P aeruginosa (17.50.7 mm) S. aureus (12.01.4 mm), E. coli (11.50.7 mm), and S. typhi (9.00.7mm). This was followed by the ethanolic leaf extract of F. exasperata which showed zone of inhibition of (10.01.4 mm) on E. coli (8.00.7 mm) on S. aureus, ( mm) on , P. aeruginosa and (6.00.7mm) on S. typhi. The antimicrobial activity of Laportia ovalifolia against the organisms was minimal compared to that of S. mombin and F. exasperata. The ethanolic leaf extract of this plant had a narrow antibacterial spectrum against the tested organisms ranging from 8.0 1.4mm against S. aureus to 3.0 1.4mm against S. typhi. The MIC showed that the extracts exhibited antimicrobial properties at concentrations ranging from 12.5ml-200ml and compared favourably with Ciprofloxacine (the positive control) at a concentration of 200 ml. The results obtained in this investigation were discussed in line with the use of the plants under investigation as medicinal plants.

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